PEI Safety Report: No Astrazeneca Concerns | Science

PEI Safety Report: No Astrazeneca Concerns |  Science

Langen – The Paul Erlich Institute (PEI), which is responsible for vaccine safety, considers Astrazeneca’s Kovid-19 vaccine as good as the Biontech / Pfizer and Moderna vaccines.

However, more suspected cases of side effects were reported for the vector vaccine than the two mRNA vaccines, the institute reported in its safety report published on Thursday evening.


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The reported rate of adverse reactions in AstraZeneca was “comparatively high”, PEI reported. However, “it may not necessarily be concluded that the vaccine is more reactive, as increased reporting rates may also be related to increased media attention for the vaccine and different age groups of immunized people”.

In addition, many reports were reported as “feeling severe”, even though it was only a temporary fever, for example. For example, in the UK, according to PEI, there is not much difference in the reported side effects of various vaccines.

Undesirable reactions after vaccination with one of three products are “mainly temporary local reactions and normal reactions”, PEI reported. These were also reported in clinical trials prior to approval. AstraZeneca reported mainly fever, chills, and flu-like symptoms. “Isolated anaphylactic reactions” should be discussed “after this vaccine”.

The Astrazeneca vaccine is now also recommended for people over the age of 65 in Germany. The Permanent Immunization Commission (Stiko) announced in advance in Berlin on Thursday that vaccination with the agent was “recommended for all age groups according to approval”. In late January, Stico initially recommended the vaccine only to people between the ages of 18 and 64.

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The PEI report includes reports as of 26 February, that is, about two months after the start of vaccination in Germany. Since then, according to PEI, there have been about 12,000 “suspected cases of vaccine-related side effects or vaccination complications” – 5.9 million vaccinations (5.4 million with Biotech / Pfizer, 168,000 with Modern and just with Estrogena With less than 364,000)).

8368 suspected cases were reported to Biontech / Pfizer, 484 to Modern and 2,765 to Astrazeneca. In about 300 other cases, the vaccine was not stated. PEI reported, “The simultaneous reporting rate of the three vaccines was 2.0 per 1000 vaccine doses.” Overall, based on all three vaccines, 16.8 percent reported being classified as severe and 83.2 percent as non-serious.

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